Neural circuits underlying motor skill learning and execution

Bence Ölveczky
(Harvard University)
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Date: November 26, 2018
Description:
I will introduce a motor skill learning paradigm that trains stereotyped complex motor sequences in rodents. By recording and manipulating neural activity in the basal ganglia, motor cortex and thalamus, we delineate the logic by which these circuits work together to promote the acquisition and control of task-specific motor sequences.
Further Information:
[1] Otchy, T. M., Wolff, S. B., Rhee, J. Y., Pehlevan, C., Kawai, R., Kempf, A., . . . Ölveczky, B. P. (2015). Acute off-target effects of neural circuit manipulations. Nature, 528(7582), 358-363. doi:10.1038/nature16442
[2] Kawai, R., Markman, T., Poddar, R., Ko, R., Fantana, A., Dhawale, A., . . . Ölveczky, B. (2015). Motor Cortex Is Required for Learning but Not for Executing a Motor Skill. Neuron, 86(3), 800-812. doi:10.1016/j.neuron.2015.03.024
Created: Wednesday, November 28th, 2018