Interactions between nervous and vascular systems in the CNS

Chenghua Gu

(Harvard University)

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Date: January 8, 2018

License: CC BY-NC-ND 2.5


My laboratory studies the interface of the nervous and vascular systems. Proper brain function depends on two unique features of the brain vasculature. First, brain blood vessels form the blood-brain barrier (BBB), which maintains the brain’s chemical milieu and ensures proper neural function. Second, neural activity rapidly increases local blood flow to meet moment-to-moment changes in regional brain energy demand – a process called neurovascular coupling. I will share with you our current and future work to understand the molecular and cellular mechanisms underlying BBB and neurovascular coupling.

Created: Tuesday, January 9th, 2018